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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1db2d2b19fdde8cb29c16aeb4daa06fdf4870545762f2466d303c74e6b6d1cbc' 
  AND token = '1IUYXVj/HlY2P8eN6u7NmVaAx9cCfQIxZWeLig9mtwU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}