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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9bb649cecfe13549ef8294433857ff009d4d62f716b77489f23cdba1ff0f0e08' 
  AND token = 'JUV+UK8lJ0xmhj9y72quc9IIEc5cDsb4t4lLSDdOE2Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}