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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e57ad9a77ca1a262f0daede7d13a4a6952498d2663636f12ae83c1fe23b92d78' 
  AND token = 'l7kWqx2OWPrnBB/zHkl1dM64qVpO80xzzNfUiuJDLUI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}