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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b887766482e439d6e800d6677ffeb7cf81abbe88a44280ce91be65c8fcb1c0d' 
  AND token = 'dCPMYZ2tER1UEFl5KXxfLhMsHl4VUptAQIQ3MYFCE0o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}