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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f50f7dc15f7ac80f7453e2ec57d1110154cee2cdca907402b7e9163243e82316' 
  AND token = '8ObCCIuvw9nby7x8LxUX3TFmdbK2pqap4UndvAOvTsE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}