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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52eb87ca8efa73b54911f627d29ff53db5a42dace29a32e95fbe68f40ac36cf9' 
  AND token = 'vmN9qyhg3GSQ7PqS++GZW427x28cj9JFGoEis7BnPaY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}