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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '421731d93cf786fe9cd34300a1015df103d36ee664ed86a66d2da8a91a7077b7' 
  AND token = 'GZ9j8gkJPNRmg4NocdCASlfaN7t9yQEXMYkz3wWpmx4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}