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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '159c81f7ce450beaaa5cd825a67f45a3a02252c676dada209c025be64f2b6a3d' 
  AND token = 'ESUzYKzjF0sPYJb2ezbhaTDpup+cwc4jPyHf30yaQVs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}