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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04d977419a0d55188a44da5b0f9d1a0f1ecadfc15623ddd923479dfac4d959f6' 
  AND token = '5UAk270VrYx6RX+w/Df9za72obTJiykMBMpqhjKVC34=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}