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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5450abd72dea297d48b3cb60b51e0f0816d312c868ab8009b7d9b5c98d407c0d' 
  AND token = 'RCVePa+aydd9Bjc0SJFa0WU4Q4fCpJ3rA2m8xPjEbbk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}