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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '955c74c71d3af3f606ea8700ad883f1d50bf8c64789aca9b3491f757ad39b0f2' 
  AND token = '+jp25cr+trhib5o9tIA0fanHMEhjztaGmZM00xs2ReY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}