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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5aaff06531f9bc4f8efde69027b13358794603050b9445e44bc3c0ac7a5e081' 
  AND token = 'nAE6xd9s3YMR5nqVpLk1njCtsYnzwZpigpqTQDT6rY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}