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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6ac016c1d1e11db871f3dd66c7784b2dbd11fa1f088414a2511c40d519d7e98' 
  AND token = 'HoX+T3BMsldUzKCEF9SjOSz7aVcU4Hk4VHnm2s+a3gs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}