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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e351f947a537e51510b736362888d894dd7fb55a907f6a33768a760182598c0d' 
  AND token = 'ed7FxR4ynKW+iMNZc0cIvgDcyb3riQLdw1tZgzA1+ZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}