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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8506f306570965060e43d2065b3dd7128ced7b72b1ebe3d8cf76fa2e411572c1' 
  AND token = '485OouNA2GfqlPbFiPQXXEsLdN+gdqv1UXiffNcF7PM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}