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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7c8d5afb0a2363b23c6da144023ff99432d511b972bcf1a5f0de70520c0b021' 
  AND token = 'w3ptjBfWh3GJKdoV0qTjVSJzK+cE4k1LCFk3gB2rR68=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}