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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '627a1a6bae65a19b44701d0eb266a3ff8eaab1ddd9c45c4cf74e9d4b3b817872' 
  AND token = 'Ejvb+6M+UidkP65VkWvtO8p6N2bOF9m9zPyC7EUXG3w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}