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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef7cb1be47d1164603c1b9f639cb0e6b6335197af17f59afdad3de1b64842065' 
  AND token = 'cwkR0QG4KIbdFYyZkJPtB4UfgXWgfP+7wgdRx0FeFOk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}