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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fbc51e7d3dc1b9a80de4f9b2b6cc7e017bb7a56b90522ffc92963a360262c04f' 
  AND token = 'IODp1jiR6+VlvBk6UltNdZfsHc5380PCqNf1C0hgZRk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}