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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '652f12832225f423c211eafd24c26deddd8a8b6907e13d80a969850ab948f0fa' 
  AND token = 'qSyKoI+gN3keY+E/n9EzK8LjON7DxESdigll+kQHllc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}