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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '71721a1fc3ffe332770ae5251a63b17aa86ad1a9374b8300e0e6f1cebae5058f' 
  AND token = 'zariTarDnA2EbcFN9oeLhomb4G/9daV6wwL1KT+ifSo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}