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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df4786180ce7c36490dee1fece5bd19dd9cf276ab6464aa98b61f3e80df4defa' 
  AND token = 'GlNFR0HMeJcv8rQWgvTQn1vOHIonj4s02E3Pt4YYtpU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}