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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5eace86d7349dfb08c5df0d2b10fcd830ef500f34781d27000d8855f9aa66602' 
  AND token = 'JOrVc+Nhs+nXyaWwHKDTKCf29hAVnaSyscLmtQL19ro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}