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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e4ac849d7bd4528ef04c7b059aa2e47e8c365af445c5b84b2b020a2e861b822' 
  AND token = 'cE+9pCK72ZkeNdnbGbz/zWx4ujP7okxIWvM3r1otPIE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}