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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af46f755b863d34f8d45d3cbe4dd173fc7a4e24c16b5700b9c4fc1a26f8447f2' 
  AND token = 'ylnS6avKdcsnsXeDvkIg6XzEEmQ0L3sCkcVcZVe3FxY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}