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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ff8ac36fdedfb9043e3b3bc149b97d037c644e809be42c13d2239aec017b25c' 
  AND token = 'd4qS2p2YXUViqItKwGrbc+Dv1Np3kY6Jv+54cvWSb+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}