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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c306d758c9b0dd710b2a9220929c7ccdfb46df7bc74f1e3f4f44e82e786dde5a' 
  AND token = 'Ldot8UT4dpCCQH2K4L+cE+1oyADqBHIpCDqTIEKBxxo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}