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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3388476e251324c641e6e8d2f099c71e299faf9b52d8d079204c1053c5750c98' 
  AND token = '+ZHNKS0hAp0qHRcN8ykoHy3I2vbSj1mVNMvtyG77Hyo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}