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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fa1be9b69c84c9bc834343bb4d1bc7e926719ee0c24c02fcfce2045748dc2d2' 
  AND token = 'rS5dRdbT+jHUUyybzZ7xvWsCPYUV4+04xCXrZ/vzU0c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}