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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2237c48fca68792d3c78e173f9c96f1a8de1eff80463d32f504bd0243a9b3394' 
  AND token = 'fKarrRsm4jDFqLL1d/jQgXWH77JOk4O4p7soLCNkHco=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}