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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53b3623ffc2667bf00e4c46c70f49ba9637c2f077d8f6e2efd2d00101d8b7017' 
  AND token = 'PXNVMzcKc8zk/o1DWdYDZEfuggBGh5/9UcbDc4CM1lg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}