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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64a60c4f536182ca07590828972893c1bc3a178d0a5902bd4d48cddda3203128' 
  AND token = 'XTTWjHemmZcWGKbLbQ3SArHZN/IVYDnidLqj9EYxRUE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}