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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '177c15b4d7cb5d49859c3e457e6ff8b04c6e1380672fcffc2f5b11129ceb96ad' 
  AND token = '1uv4KbDuzBJzd7e22/dQjpyxFNZcFC7fPk2SHZYLl4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}