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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b0874ab5be7198b08fbe333c5be67c1b3d4f15f8e93afcb597c510c8b0762d7' 
  AND token = 'EgRBNxHfAceRkmVbpg6UnxWJXVMBBAmqFcWBGMfeaIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}