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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1de03d1247cb4e0ee31ed6f2e6212046f610286d3682c5f35752c647c574e6f5' 
  AND token = 'Cd8PZHT/H0iY9+S2bz15dRUyELAcxc4uTu83t66L7Zg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}