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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3881e8671fdfd62d59242acb7d003d547cf5c238520f2c8e631f1c5f6950ac7c' 
  AND token = '3UK0DRfBpVh8XHAuF3FKNcCnoMdbtMNRcGEXzT2s/lA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}