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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66f20f6722e09ef2289ac319db9d0a3232c269228dc9fbc8578ced65fe640d9c' 
  AND token = 'jGQLUvx6gixeZw7GUehM0+H7/1kBtTnGV/jQbQ38JOA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}