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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b3da3e9e4ffbc55e8e32865c1da45d0e8e295fb1f643e90122c06db221158e5' 
  AND token = 'NMWIWF6lEw6fIhl5ldTQ6nbAhFVgbpp9dxRHlz4VSck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}