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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ded74ccb5cec7b349732a506334a79979108f5e14e96a0cd46d4a8f128dbaef' 
  AND token = 'RxxIrMhKfnClhU/fd5YTe8pP+sa2S20wsPnWFyBSEvw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}