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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c166a48a75aab8a10321ca82dcc3efce6f5bf6714bb295779e65506cb48a0444' 
  AND token = 'OYpZ+StwHnyRocXJH+C1SjZUcFnstnW1+ljYMsdKe8w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}