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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f52704782aecc658b00bc0e80d400e81608b0005b6b0e106fbbb7b2fddfbf08b' 
  AND token = 'PNKG/9xlsYMDLFR/eLKlL6YV7TdHfTkPmMGKdXVAroY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}