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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f4b7a1df360d805c84810e468d31790fc1155181ba6773ce493362c2326c2fc' 
  AND token = 'UCz/ZakaNjt0BZZ7o4BmFa2dVTBZ+UHxjfs5zhRIcNk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}