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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4271d586cfaae274cb3b0bdbdf5f84528b1127718d5deb5927d39e23775eef4' 
  AND token = '6NlGVwaOHDi7g7DCAcIjLMPTSD9PxPPnjP+8xbv3Tmw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}