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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8050976ad5076f9c99b33d5cfd662172c5489c7154704418131c597c634e4032' 
  AND token = 'R/28NPJ4T/I5Nt3famZ/n/VMdaqLTfDHQKtT65uCa9E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}