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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cfb248bb1e517e167c9e39359fcb1652b5ea9b4802d72361102753146ed2898' 
  AND token = '+YClIedD/esffMhQWyy0v5tYxmmlLT1bNAUbNbnboX8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}