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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d82f2d1ec8081b4754f4990592274f0e0439f3b3fd0e1e86c67cd2165a01189' 
  AND token = '2h6sq1EBXIJVHH27RdDSXbcGpT/XKCAV2X+gTrtRyAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}