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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b146740c15735e84aaaa126bbb2d8be4c5a365c2d3eb934813470c14dc7b27a5' 
  AND token = '5GT2hoLkj1CCts12RVn0I0PeKZY/9e4mi7zmFjxvTKM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}