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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fdde66bf7b19a3f015fb28018417d4f38f2060fbae6501107c464ba1899ff61' 
  AND token = 'aNrX7IjMA/IiQZzN4I7uJBQ0tgWzZP2aFF9JLMonKtM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}