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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88b8f50b3cc32d71dd7bbfc93b9897ff31589e9f318960b7681dfbdfaac8a3fa' 
  AND token = 'FPZPdGliXsceDNSVva64I1CrtT5hcVT/o5nKS/gbViI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}