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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3221aad10b7a03c12c4cb6bde9abdaed562a99da76251688133a235e4ae8491d' 
  AND token = 'L6y7ICLVXknHmR25X2Kvm3ZQ+5fUA5JG80E0pekkrb0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}